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CT scans may show characteristic findings such as ground-glass opacities in centrilobular distribution, and mediastinal lymphadenopathy , but these findings are non-specific and may be seen in other conditions.

However, pulmonary hypertension revealed via physical examination , in the presence of pleural effusion done via CT scan usually indicates a diagnosis of pulmonary veno-occlusive disease.

The prognosis indicates usually a 2-year 24 month life expectancy after diagnosis. Treatments for primary pulmonary hypertension such as prostacyclins and endothelin receptor antagonists can be fatal in people with PVOD due to the development of severe pulmonary edema , and worsening symptoms after initiation of these medications may be a clue to the diagnosis of pulmonary veno occlusive disease.

The definitive therapy is lung transplantation , though transplant rejection is always a possibility, in this measures must be taken in terms of appropriate treatment and medication.

Pulmonary venoocclusive disease is rare, difficult to diagnose, and probably frequently misdiagnosed as idiopathic pulmonary arterial hypertension.

Prevalence in parts of Europe is estimated to be 0. PVOD appears to occur as frequently in men as in women, and age at diagnosis ranges from 7—74 years with a median of 39 years.

From Wikipedia, the free encyclopedia. Shortness of breath Fatigue Fainting Hemoptysis Difficulty breathing lying flat Chest pain Cyanosis Hepatosplenic congestion.

Retrieved 31 July Retrieved Eur Respir J. Intern Med. Pulmonary Pathology. Elsevier Health Sciences. Genetics Home Reference.

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